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Today, oncological diseases occupy second place in the structure of mortality of the population after pathologies of the cardiovascular system, and drugs for oncology can be purchased in almost any pharmacy. In men, lung cancer is the most common, in women – breast cancer. Frequent morbidity is due to the complex influence of negative factors (physical, chemical, and biological) that disrupt the structure of DNA and provoke the appearance of tumors. The medical community is currently actively developing new effective oncological agents.
Oncology drugs can be purchased at a good price at Peptides Warehouse. Cancer pills have a huge number of side effects and should only be used as directed by your doctor. Strict adherence to the doctor’s instructions and recommendations will improve the prognosis for recovery.
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How close are we to finding a cure for cancer? With each new discovery, it seems that this is – hurry. And now cancer has been defeated and is no more dangerous than the common cold.
But. Once a new drug reaches patients, it turns out that everything is far from rosy and there is still a very long way to go.
However, if we compare the possibilities of medicine for treating cancer 15 years ago and now, the difference will be impressive. New anti-cancer drugs have given patients years to live. And often a full life. With diagnoses that in the early 2000s it was possible to live with only a few months, you can now count on 5-10 years. And for some cancers, doctors, though still cautious, are talking about a full recovery.
And this is the merit of the new drugs based on the genetic and molecular mechanisms of development of malignant tumors, discovered in recent years ..
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In Belgium, as in other European countries where the recommendations of the European Community of Medical
The most commonly used drugs for targeted and immunotherapy this year in Europe are 10 drugs.
- Revlimid Celgene (Lenalidomide) – Prior to the development of Revlimid, the prognosis for patients diagnosed with multiple myeloma was poor, so the survival rate increased within a few years of starting the drug.
- Herceptin (trastuzumab) is a monoclonal antibody developed by Roche. The breast cancer drug is administered by injection and acts by binding to the HER2 receptors of cancer cells to stop their growth. The biological analogues Tranzimera (USA) and Ontruzant (Europe) were approved in 2018, providing patients with greater access to this vital drug.
- Avastin (bevacizumab) is a medicine based on monoclonal antibodies. It works by reducing the supply of oxygen and nutrients to the tumor and preventing the growth of new blood vessels. It is able to successfully treat various types of cancer, including tumors of the kidneys, cervix, ovaries, and brain.
- Rituxan (rituximab) is a monoclonal antibody that is used to treat many types of blood cancer, including non-Hodgkin’s lymphoma and some leukemias, as well as other conditions such as rheumatoid arthritis and vasculitis. The antibody acts by binding to B cells, leading to cell death (apoptosis).
- Keytruda (pembrolizumab) – This medicine consists of antibodies that increase the body’s ability to induce an anti-tumor response that helps it attack cancer cells. It is approved for the treatment of many cancers, including non-small cell lung cancer, classic Hodgkin’s lymphoma, melanoma, cancer of the stomach and cervix. In 2019, Merck announced plans to accelerate the use of Keytruda to treat prostate, head, and neck cancer. Tests show a 44% reduction in the risk of death or worsening of Keytruda disease.
- Zytiga is a hormone therapy drug used to treat prostate cancer, the most common cancer in men. It treats patients with prostate cancer that has spread to other parts of the body. Because prostate cancer needs testosterone to spread, Zytiga works by blocking the enzyme cytochrome p17, which helps produce it. This causes the tumor to shrink or slow down. The drug not only prolongs life, but also improves the quality of life by reducing pain and improving mental and physical health.
- Imbruvica is a tyrosine inhibitor. The drug is used to treat various types of B cells, such as mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenstrom’s macroglobulinemia (a type of non-Hodgkin’s lymphoma). According to a recent study, patients treated with Imbruvica had a much better quality of life than those treated with similar drugs. The drug also has an excellent side effect profile and is well tolerated by patients.
- Opdivo (nivolumab) are monoclonal antibodies that stimulate the body’s immune system to kill cancer cells. The drug is approved for the treatment of many different types of cancer, including skin, lung, head and neck, bladder and classic Hodgkin’s lymphoma. Efficacy studies of Opdivo for various cancers show that it prolongs the life of 73% of skin cancer patients, 66% of lymphoma patients, and 66.5% of bladder cancer patients.
- Ibrance is a targeted biological therapy developed to treat breast cancer (the most common type of cancer). The drug is approved for use in advanced and secondary cases of breast cancer and is used in combination with hormone therapy.
- Neulasta – This medicine has been specially developed to fight the side effects of chemotherapy for breast cancer, neutropenia, which makes patients vulnerable to infection. Neulasta works by stimulating the bone marrow to produce more white blood cells, which help the body regain its ability to fight infection. The drug is effective in reducing the duration of severe neutropenia to 1.7 days instead of 5-7 days.
Chemotherapeutic drugs do not lose their relevance. Today, 5 groups of drugs are most widely used in European cancer centers.
- Alkylating drugs (damaging the DNA of cancer cells) – carboplatin, cisplatin and oxaliplatin.
- Drugs that disrupt the metabolism of cancer cells – 5-fluorouracil, cytarabine, gemcitabine and methotrexate.
- Drugs that block DNA-activating enzymes in cancer cells that help them divide and grow are daunorubicin and doxorubicin.
- Mitosis inhibitors – docetaxel and paclitaxel.
- Topoisomerase inhibitors – irinotecan and topotecan.
Every year, the list of cancer drugs is updated with new promising drugs, which brings oncologists another small victory.
We invite you to get acquainted with the most interesting innovations of cancer drugs that will be used in 2020, to find out what drugs they are and what will bring their appearance in clinical practice. All these new drugs and treatment regimens have already been approved and approved for use in clinics abroad – in Europe, the United States, Japan, and Israel. They are also available in clinics in Belgium.
Of course, such drugs can be used only under the supervision of a physician, within an individually selected treatment regimen. Only a specialist can prescribe a drug for oncology after a complete examination.
Novelties in cancer immunotherapy 2020
This is a form of therapy that uses biological methods to fight cancer. Immunotherapy drugs are:
- checkpoint inhibitors that interfere with cancer’s ability to avoid detection by the T cells of the immune system.
- some monoclonal antibodies that, attached to certain cancer cells, reveal their foreignness to the immune system. then it kills these cells.
- cancer vaccines that improve the ability of the immune system to recognize and destroy cancer-specific antigens.
- Cytokines are special proteins that play a key role in the ability of the immune system to respond to cancer invasion.
