Peptides Therapy: As the endogenous (body) proteins of the immune system can be obtained from dietary proteins, all proteins, respectively. their peptides and amino acids are important for their maintenance. In the US, where whey protein isolates have been paying particular attention in recent years, it has been found that over 90 percent of proteins are significantly immunoreactive if they have a high level of denaturation.
Meanwhile, many other studies show that almost all peptide therapy proteins hydrolyzed (and thus intentionally denatured) to short-chain peptides are immunoreactive. However, whey and wheat protein hydrolysates having a high content of glutamine (which enhances the overall immune protection of the body) and/or cysteine (which accelerates SOD synthesis) have been recognized as particularly active in the immune system.
Mental Functions Associated with Peptides Therapy
It is a well-known fact that dextrose and/or caffeine increase the concentration, but the effect is short-lived due to the release of insulin and subsequent fall in blood sugar. The amino acids tyrosine, phenylalanine and, as recently found, a large amount of L-leucine branched-chain amino acid (BCAA) mixtures increase mental performance, making it more enjoyable and lasting. The stimulating effect is really significant and is mainly used in the United States among economists, the military, students, competitive athletes, and people whose success depends a lot on their mental and psycho-physical abilities.
Supplementation with a mix of amino acids is recommended especially in combat sports (especially boxing), tennis, football, and all related sports, but also in endurance sports. On the other hand, tryptophan and GABA are usually taken to achieve mental balance, stress management, and restful sleep. The combination of the free amino acid L-tryptophan with the bioactive whey protein hydrolyzate peptide NA6, which contains short-chain tryptophan peptides, is particularly beneficial.
In a study at the Higashi-Hankyu Bldg Clinic in Osaka, Japan, test subjects consumed normal food, all food items were allowed, and normal life habits were not altered. Peptide receiving groups received 600 or alternatively 1200 mg of short-chain globulin-peptide daily, distributed in doses of 300 and 600 mg, respectively, to the two main meals of the day. The placebo group received pseudo-effect capsules that looked the same. After three months, the peptide groups lost an average of 7%, respectively. 10% of their body fat, while the placebo groups retained the same fat.
It is curious that in this study, men lost only 0.7% of their weight, while women – 0.5%. Obviously, these peptides improve the muscle-fat ratio by breaking down body fat and accumulating fat-free muscle mass (this has also been found in various animal experiments). It remains to be noted that none of the participants in the study was engaged in intensive sports activities and according to initial practical results in bodybuilders the positive effect on the muscle-fat ratio is more pronounced.
The ability of short-chain peptides to reduce triglyceride levels was demonstrated in a study by Kagawa et al. Conducted at Ehime Medical University, Japan. Even with a high-fat diet, peptides have been shown to reduce blood fat by 40%.
In the animal experiment, the biological activity of various peptides was examined in relation to the construction of fat-free muscle, respectively. burning fat. The following results were obtained with normal (high fat) nutrition:
Peptide type Bodyweight in g Fatty tissue in g Pure muscle mass in g
Without peptide 36.5 (29.0) 2.0 (1.8) 34.5 ( 27.2)
Blood protein 36.9 (29.2) 1.6 (1.4) 35.3 (27.8)
Fish protein 34.8 (29.3) 1.3 (1.3) 33, 5 (27.0)
Soy protein 36.9 (29.3) 1.8 (1.4) 35.1 (27.9)
The values in the brackets show the results in the female animals. Obviously, short-chain peptides improve the absorption of dietary protein (increase lean muscle mass) and differently alter body fat content.
The reasons for the variation in fish protein hydrolysis have not yet been clarified.
In Terumo Corporation patent 59076022 A, it has been demonstrated that certain short-chain peptides can increase the level of nitrogen uptake in humans and lead to significant muscle mass gain by improving nitrogen balance.
Many other studies indicate that the action of short-chain peptides is not species-specific. In fish as well as in pigs, the addition of peptides to the diet led to a reduction in fat in the meat, an increase in muscle, and an improvement in the taste of these animals used in food production.